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2019/03/30, Volume 1, Issue 1, pp 59 - 64

Synthesis of Schiff Base Metal Complex: Characterization, Antioxidant and Antidiabetic Studies

R. MUTHUKUMAR @ SIVARAMAN M. SELVIPRIYA

Abstract

A new Schiff base was synthesized by condensation of benzaldehyde and urea. Schiff base metal complex is prepared with Zinc Chloride salt. Schiff base and its Zn(II) complex were characterized by Fourier Transform Infrared Spectroscopy (FT-IR). The spectral results confirmed the formation of the ligand and metal complex. Both the schiff base and its metal complex were tested for antioxidant activity which showed moderate activity. The antidiabetic activity of the Schiff base and its metal complex were tested by Alpha amylase inhibition assay method. Between the Schiff base and its metal complex, Zn(II) complex showed good activity and Schiff base showed moderate antidiabetic activity.

Keywords

Schiff Base, Metal Complex, FT-IR, Antioxidant Activity & Antidiabetic Activity.

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